In the combined analysis of the DELIVER (Dapagliflozin Evaluation to Improve the Lives of Patients with Preserved Ejection Fraction Heart Failure) and DAPA-HF (Dapagliflozin and Prevention of Adverse-outcomes in Heart Failure) trials and the DEFINE-HF (Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients with Heart Failure with Reduced Ejection Fraction) and PRESERVED-HF (Effects of Dapagliflozin on Biomarkers, Symptoms and Functional Status in Patients with Preserved Ejection Fraction Heart Failure) trials, there were consistent benefits of dapagliflozin on both clinical events, as well as health status across the spectrum of LVEF, with no suggestion of attenuated benefit at higher LVEF
HSA and FSA cards are a different story, and the answer is it depends on your plan administrator
But contact your provider if you experience severe or persistent pain at the injection site lasting more than 48 hours, signs of infection such as increasing redness, warmth, swelling, or pus, severe nausea or vomiting that prevents you from keeping fluids down, or any symptoms that feel significantly different from your normal semaglutide experience
doi: 10.2165/00002018-200831010-00005 29 BillesSKSinnayahPCowleyMA
He never hesitates to refer me to a specialist if he feels I would benefit more