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LLY's long-term uptrend remains intact

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Research shows that five GLP-1s account for 16% of the overall prescription cost for the Rx Collaborative, the largest pharmacy coalition in the U.S., after estimated rebates and discounts in Q1-Q3 of 2024, a rise from just 1% in 2020

Seek immediate medical attention for: Severe, persistent abdominal pain, especially if different from typical IBS pain or radiating to the back (possible pancreatitis) Persistent vomiting preventing adequate fluid intake Signs of dehydration (decreased urination, dizziness, extreme thirst) Severe constipation lasting more than 3-4 days without bowel movement Blood in stool or black, tarry stools Yellowing of skin/eyes, right upper quadrant pain (possible gallbladder disease) Markedly reduced urination (possible acute kidney injury) Fever accompanying gastrointestinal symptoms Neck mass, difficulty swallowing, persistent hoarseness (thyroid concerns) Allergic reactions (rash, itching, swelling, severe dizziness) Scheduled follow-up should occur within 4-6 weeks of initiating therapy and after each dose escalation

The article's timeline table puts onset at days one to seven after a dose increase, with cramping peaking during weeks two to four and showing gradual improvement by weeks six to twelve