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While there are several types of these receptors, like VEGFR-1, VEGFR-2, and VEGFR-3, it appears that the primary mediator of angiogenic response is most likely VEGFR-2

It may also help with improved muscle recovery as well as decreases in lactate, creatine kinase, phosphorus, inflammatory markers, and improved glycolytic/ fat oxidation markers

The Liver-selective TR knockout mice (LTRKO) were generated by cross-breeding of TR Floxed mice with mice harboring Cre-recombinase under the control of the albumin promoter (Alb-Cre mice)