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A vast number of preclinical and clinical studies have provided evidence for the potential role of GLP-1R agonists in modulating reward-seeking of food, alcohol, cocaine, and amphetamine, offering the possibility of a novel therapeutic alternative for treating addiction [112]

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Le groupe acyle fix sur le CoA peut prsent tre transfr sur la carnitine, et l'acylcarnitine rsultant tre transfr travers la membrane vers la matrice mitochondriale

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Native GLP-1 has a short half-life due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) ( Figure 1 In recent years, growing evidence has highlighted a bidirectional interplay between GLP-1 RAs and the gut microbiome

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They may work by increasing VEGF and Nitric oxide this may leads to new blood vessels and there is increase in blood flow to injury

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