An analog of MOTs-C called CB4211 was studied in a small phase 1 trial in obese patients
It improves mitochondrial function, AMPK activity, and insulin sensitivity
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The review highlights its pleiotropic beneficial effects in tissue injury, inflammatory bowel disease, and CNS disorders, and concludes that BPC-157 demonstrates a favorable safety profile with few reported side effects, positioning it as a candidate for further clinical investigation
Some fatigue signals something more serious