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Taking too much of some B vitamins may have adverse effects, like diarrhea, rashes, and headaches

Mood may be affected

The combo is generally safe when monitored by a healthcare provider, though side effects like nausea and mild GI upset may occur

thus, Se acts synergistically with vitamin E through its role in the GPX system, regenerating vitamin E (in conjunction with vitamin C) and further reducing lipid peroxides (141, 151)

In practical procurement language, this means the buyer is asking whether the supplier can support a controlled research purchase with records that can be retained in a laboratory file