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Physiological functions of carnitine and carnitine transporters in the central nervous system 4, 6
Considering these changes in T2DM and the critical role of GLP-1 in glucose homeostasis, strategies for managing T2DM based on this hormone include addressing the differentiation of L-cells, increasing the endogenous production and secretion of GLP-1 through stimulants, extending the half-life of GLP-1 by inhibiting its degrading enzyme and targeting GLP-1R using its agonists
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Oral absorption in humans is unproven, but animal studies suggest possible systemic effects even with oral dosing6
J.SrinivasN
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