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To date, dulaglutide, semaglutide, and tirzepatide have been the three predominant GLP-1 therapeutics employed in the treatment of T2DM, and their applications have been broadened to include weight management
TRIUMPH-1s cohort started heavier 112.7 kg and BMI 40.0, against 106.4 and 38.2 in TRIUMPH-2
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Gradually increase the dosage as tolerated, which may help mitigate side effects
Emphasis is placed on clinical screening, controlled titration, and ongoing monitoring to align outcomes with safety parameters
