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Importantly, a pilot study in older adults with T2DM and obesity reported that semaglutide preserved the SMM percentage of the extremities despite a decrease in total muscle mass [55]
GLP-1 receptor agonists were originally developed for type 2 diabetes management but gained popularity for their weight loss benefits
4 However, the majority of ingested nutrients are absorbed in the small intestine, before reaching the large intestine which harbours the highest density of L cells
References 1 PonticelliCFaviEFerraressoM
AMPK: positive and negative regulation, and its role in whole-body energy homeostasis
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