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Methods Ethical approval All animal experiments reported herein were performed following the guidelines and were approved by Peking University Institutional Animal Care and Use Committee (LA2021316)

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It is investigated exclusively in in vitro and animal models for understanding tissue repair, angiogenesis, and gastroprotective mechanisms

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Controlled fluorescent labelling of antibody The engineered antibody was diluted in PBS containing 2 mM CTAC, achieving a final concentration of ~0.3 mg ml 1 , and then 1455 l of the above antibody solution was aliquoted in two microcentrifuge tubes