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Their effects likely arise from a convergence of pathways: indirectly, through systemic improvements in glycemic control and metabolism, and directly, via the activation of intraocular GLP-1Rs on cells like retinal Mller and ganglion cells, which triggers local anti-inflammatory, anti-oxidant, and anti-apoptotic responses
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After she started taking Ozempic, she noticed a difference
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Finally, the important but less common outcome of nonfatal stroke was reduced with GLP-1RA, particularly in the Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN) 6 trial (semaglutide once weekly injection) and Researching Cardiovascular Events With a Weekly Incretin in Diabetes (REWIND
