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Lipid changes lag behind weight changes by 3 to 6 months
It often occurs in the morning and/or after longer periods without eating
For example, tirzepatide trials reported that up to 10% of participants experienced itching or redness
Phase 2b data shows competitive weight loss (14.1% placebo-subtracted), and the convenience of monthly dosing could significantly improve treatment adherence
Considerations: KPV particularly suits fibromyalgia patients with significant inflammatory markers or comorbid inflammatory conditions
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