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In microglia, GLP-1R activation via PI3K/Akt signaling also reduces neuroinflammation by modulating NF-B activity, decreases the production of pro-inflammatory cytokines, increases anti-inflammatory markers such as IL-10, IL-4, Arginase, and CD206, and the transformation of microglia into an anti-inflammatory state

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Currently available GLP-1 receptor agonists in the UK include: Exenatide (injectable formulations) Liraglutide (Victoza for diabetes

[PMID: 14159300] PubMed record related to this compound for laboratory literature review

This has led to a waste of time, loss of resources, and delayed diagnoses for patients