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The obvious conclusion of these findings is that we should view obesity as a medical condition, like high blood pressure, where effective and safe drug therapy can contribute to reducing serious adverse health outcomes. Novo Nordisk expects to file for regulatory approvals to expand the use of the drug to protect against major adverse cardiovascular events in the US and the EU later this year
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The efficacy of systemic GLP-1R agonists to attenuate cocaine seeking is associated with decreased activity of dopamine cells in the VTA VTA dopamine neurons mediate the rewarding effects of cocaine and increased dopamine cell firing in the VTA is necessary for cocaine seeking 58,59
Matrix Metalloproteinases: Role in Arthritis
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