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Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model

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Growth hormone secretion, which peaks during slow-wave sleep and shares some mechanistic overlap with BPC-157's proposed GH receptor effects, is substantially suppressed by sleep restriction below 6 hours per night

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Lentz SR, Sobey CG, Piegors DJ, Bhopatkar MY, Faraci FM, Malinow MR, Heistad DD

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Supporting these findings, a recent PET (positron emission tomography) imaging study by (Kato et al., 2023) demonstrated a significant reduction in Complex I availability in the anterior cingulate cortex of ASD individuals, reinforcing the hypothesis that compromised mitochondrial respiration plays a key role in ASD pathophysiology

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