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The strongest human clinical evidence is for topical use, including the Leyden 2002 photoaging trial and a 2023 NEEL gel topical study reporting an average 28% increase in skin collagen density at 3 months
Beginners should start at 250 mcg daily to assess individual tolerance and response before potentially increasing the dose
By keeping your collagen intake separate or taking it with light, easily digestible foods, you give those specific peptides a "fast pass" to your bloodstream
The peptides ability to promote endothelial cell migration and angiogenesis may contribute to improved cardiac perfusion and functional recovery following cardiac injury
AMPK: a metabolic gauge regulating whole-body energy homeostasis
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