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For CoQ10 , typical supplemental doses range from 100 to 300 mg daily , though some clinical trials have used doses up to 600 mg daily for specific cardiovascular conditions

4.2 Effects of perchlorate, dioxin and persistent organic pollutants on thyroid function Perchlorate, commonly present in both drinking water and specific food items, competitively hinders the absorption of iodine by the thyroid gland, subsequently reducing the synthesis of thyroid hormones, and has been related with decreased cognitive function in offspring (89)