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The ability of the microbiota to affect CNS activities bidirectionally through the vagus nervous system (VNS) is mainly mediated by the neurological (ANS), hormonal (HPA axis), and immunological (cytokine and chemokine) processes, all of which are interrelated (52)
20 BousfihaA.RiahiZ.ElkhattabiL.BakhchaneA.CharouteH.SnoussiK.et al (2019)
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Because the pill mimics natural hormone functions, it travels to the brain to target the reward centers that drive overeating, says Sara Velayati, MD, an obesity medicine specialist at the Fleischer Institute Medical Weight Center at Montefiore Einstein in New York
