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Conceptualization, Formal Analysis, Investigation, Visualization, Writing-original draft, Writing-review & editing Y.L

Systemic side effects may include nausea, gastrointestinal upset, flushing, and, in rare cases, allergic reactions such as rash, hives, or anaphylaxis

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This gives the neural tissue a higher susceptibility to peroxidation ( Parkinsons Disease (PD) Pathogenesis: Role of Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation Parkinsons disease is a chronic, progressive neurodegenerative disorder involving the dopaminergic neurons in the substantia nigra pars compacta of the brain ( Dopamine Metabolism The neurotransmitter dopamine itself can be a source of oxidative stress