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Very rarely, more serious reactions can occur, such as a severe allergic reaction

People with low B12 may experience: Persistent fatigue or low energy Weakness Brain fog, concentration issues, or memory changes Low mood or irritability Pins and needles, numbness, or nerve-type sensations Mouth ulcers or a sore tongue Paleness or shortness of breath (if anaemia is present) Some symptoms can become more serious if deficiency is prolonged, particularly neurological symptoms

Across those examining cancer, an elevated B12 was consistently associated with a higher chance of a cancer being present or later diagnosed