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Binding-affinity work using peptidomimetic secretagogue derivatives has characterized Ipamorelin and related structures at the ghrelin receptor, including their use as reference ligands in receptor-imaging probe design [4]
However, all of the published human studies have used R,S -lipoic acid (racemic mixture)
This makes it both economical and practical for daily use
Pre-existing endocrine disorders (diabetes, pituitary disease), because GH-axis manipulation can disrupt glycaemic control
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