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Tropical Journal of Pharmaceutical Research, 14 (10)

Yeon JE, Choi KM, Baik SH, Kim KO, Lim HJ, Park KH et al (2004) Reduced expression of peroxisome proliferator-activated receptor-alpha may have an important role in the development of non-alcoholic fatty liver disease

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Mechanistically, FA reacts with the redox-active thiol group of glutathione (GSH), altering the GSH:GSSG ratio and causing oxidative stress