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Tirzepatide reacts to temperature shifts, and wrong storage conditions might lower how well it works
In terms of its effects, it appears to impact drinking in ways (though not necessarily mechanisms) similar to naltrexone (FDA-approved) and topiramate (prescribed off label for alcohol use disorder), which have a greater effect in reducing intensity of drinking on drinking days relative to their effects on whether someone drinks at all (i.e., abstinent days) although all of them do increase abstinent days to some degree on average)
B-Complex directly reduces GI distress
If fatigue persists despite these interventions, or if it is accompanied by other concerning symptoms, further medical evaluation is warranted to exclude alternative diagnoses
10.3389/fnut.2015.00023 44
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