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The dosing schedule is always tailored to each patient to balance effectiveness with safety and comfort
The increased risk of DKA in the SGLT2i group, and the associated hospitalisation, was not great enough to offset the increased rate of hospitalisation of any cause in the GLP-1 RA group
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The available window for an agonist to produce a measurable increase is compressed, because half the signal is already spent, so a genuine agonist effect can look smaller than it is
Retrieved 16 December 2021
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