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But if they become severe or persistent, working closely with a clinician to pause treatment or lower the dose can help

1B) wild-type flies exposed to APAP at a concentration of 100 mM, 50 mM, 25 mM, 12.5 mM, or 0 mM (vehicle control)

Most headaches are mild and respond to standard headache management approaches, but persistent or severe headaches should be evaluated

Drugs with miraculous benefits require very few patients to meet bars for statistical significance

The bar for NHS commissioning is high, requiring demonstration of meaningful benefit over existing options at an acceptable cost per quality-adjusted life year (QALY)