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Direct effects on cellular proliferation A genetically engineered murine model of pancreatic intraepithelial neoplasia (PanIN) to PDAC progression ( LSL-Kras G12D ;Pdx1-Cre, KC ) treated with exenatide demonstrated architectural changes of loss of polarity and micropapillary formation following 12 weeks of therapy 18
Anal Biochem 1983
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Baghban et al
Impacto en la prdida de peso: Los mimticos de GLP-1 ofrecen un enfoque teraputico dual, centrado tanto en el control de la glucosa como en el manejo del peso, lo que los convierte en una opcin valiosa para el tratamiento de pacientes con obesidad , diabetes tipo 2 y sndrome metablico
