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Mental stress impacts the nervous system and elevates cortisol levels which promotes energy storage and invites food cravings for ultra-processed comfort foods

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-Based E3 ligase to regulate proteasomal degradation of Nrf2

This can be seen in levels of vitamin B12 detected in the brains of subjects with normal serum B12 levels as they age (Zhang et al, 2016)

BPC-157 fills this gap by promoting tendon and ligament healing, reducing inflammation, and supporting gut mucosal integrity (relevant for patients on medications or supplements that may stress the GI tract)