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These trials have targeted various groups, including individuals with diabetes, focusing on cognitive effects, and those with or at risk of AD or PD (summarized in Table 2 for AD and Table 3 for PD)

Ad esempio, nello studio STEP 1 pubblicato sul New England Journal of Medicine nel 2021, i partecipanti trattati con semaglutide una volta alla settimana hanno perso in media quasi il 15% del loro peso corporeo iniziale

Stable gastric pentadecapeptide BPC 157: Novel therapy in gastrointestinal tract. Current Pharmaceutical Design (2011)

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Recently, two randomized controlled trials (RCTs) demonstrated that tirzepatide, a dual GLP-1/GIP receptor agonists, reduced the AHI and hypoxic burden, and improved sleep-related patient-reported outcomes among individuals with moderate-to-severe OSA [24]