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In the Billon 2023 paper, mice given 30 mg/kg IP still showed measurable plasma and muscle concentrations at 6 hours post-injection, which helps explain why twice-daily dosing was used in efficacy studies

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Search Within Type of Search Limit to a Database Search Databases Manually by Outline Summary: It is now known that some medications, when used chronically, can result in undesirable side effects that were not necessarily obvious or present within most initial clinical trials

Heres why: there are nuances to each product that does truly make some products better-suited to particular treatments and/or cases