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The exact mechanism by which semaglutide benefits knee OA requires further study, but initial results show great promise: A mean change in knee pain, which was assessed using the WOMAC criteria for pain scoring , demonstrated a reduction of 41.7 points for semaglutide and a decrease of 27.5 points for a matching placebo

Zhang W, Watson CE, Liu C, Williams KJ, Werth VP

However, they are not a substitute for professional medical advice, diagnosis, or treatment

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Versus semaglutide alone Semaglutide 2.4 mg (Wegovy) produces approximately 15 to 17% weight loss in clinical trials