OCN is a small c-carboxyglutamate protein, which is synthesized only by mature cementoblasts, osteoblasts and odontoblasts, and its function is controlled by RUNX2 in the later-stage of mineralized tissues 35,36,37
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The research literature describes suppression of pro-inflammatory pathways and support of antioxidant defense systems, contributing to its characterization as a broadly cytoprotective copper peptide 1
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Our data showed that JMF4073 sensitivity was inversely correlated with the cellular levels of GSH