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The mechanism involves improved fat oxidation rather than appetite suppression

doi: 10.1038/s41581-022-00658-w 135 LuoYLiuLZhangC

Couture Med Spa reports a similar pattern among its own tirzepatide and semaglutide patients, listing mild nausea or upset stomach, temporary irritation at the injection site, fatigue or headaches, and changes in appetite, and adds that most side effects fade as the body adjusts to treatment (couturemedspa.com)

Bibcode:2009EnvMM..50..285S

Computational details Structure GAUSSIAN 09 28 program package is employed to carry out density functional theory (DFT) calculation to find out the optimized structure of carmustine molecule