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Trial data consistently show the combination arms exceeding cagrilintide-alone arms 15.6% vs 8.1% at 32 weeks in the Phase 2 diabetes trial (Frias et al., 2023), and a 22.7% combination figure at 68 weeks in REDEFINE 1 (Aronne et al., 2025)

Reappraising the relationship between hyperinsulinemia and insulin resistance in PCOS

By modulating inflammatory responses, GLP-1RAs can help prevent the degeneration of dopamine-producing cells

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Severe deficiency may lead to anaemia or nerve damage