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In addition, extracellular lactate stabilizes HIF-2, and HIF-2 then transactivates MYC, increasing the levels of glutamine transporters and GLS1, in turn resulting in increased glutamine catabolism 72

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How long does it take to notice changes with supplementation

The demographics and cohort characteristics, none of which are significantly different between groups, are presented in Table 1

While IGF-1 plays a role in muscle repair and satellite cell activation, outcomes depend on nutrition, recovery, hormonal balance, and overall health