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Ferroptosis is strikingly driven by worsening redox imbalance, which generates and maintains high levels of hydroperoxy-phospholipids (7, 24)

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To explore the effect of the TRIM28 double-KR mutation on PGC development, we first generated a K774R + K779R AG-haESC line based on Blimp1-T2A-Cre cells (Fig

A deficiency in vitamin B12 results in an insufficiency of mature red blood cells containing haemoglobin, the oxygen carrying pigment that distributes oxygen to all the tissues around the body

This feedback-driven optimization enhances both the predictive reliability and practical applicability of the model