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An increase in glutathione level may induce the pigment cell to produce pheomelanin instead of eumelanin pigments

The distinguishing features of infection versus simple inflammation are progressive worsening beyond 48 hours, spreading redness with clear borders that expands outward, red streaks radiating from the injection site (indicating lymphangitis), warmth that increases rather than decreases over time, pus or cloudy discharge from the site, and fever above 100.4 degrees Fahrenheit (38 degrees Celsius)

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J Am Acad Child Psych