Scientists have found that GLP-1 peptides, once mainly linked to blood sugar regulation, also influence appetite, inflammation, and aspects of brain function
136 1701-1705 (American Institute of Nutrition, 2006)
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Likewise, PET-CT scans of mice fed a high-fat diet (HFD) showed that metformin increased glucose uptake on the basolateral side of the intestine, leading to enhanced glucose tolerance in a manner that depended on the dosage (Tobar et al., 2023)