EMBO Reports, 2 (4), 282-286
Retrieved from: 2 Montero, Alex et al
Gli eventi avversi gastrointestinali nausea, vomito, diarrea, costipazione sono stati i pi frequenti, riportati nel 74,0% dei trattati contro il 42,2% del placebo, con il profilo gi noto della semaglutide
When considering adding a GLP-1 receptor agonist like Rybelsus, NICE guidance indicates these agents may be appropriate for people with type 2 diabetes who: Have a BMI of 35 kg/m or higher (adjusted for ethnicity) and specific psychological or medical problems associated with obesity, or Have a BMI lower than 35 kg/m and for whom insulin therapy would have significant occupational implications, or weight loss would benefit other significant obesity-related comorbidities GLP-1 therapy should only be continued if there is a beneficial metabolic response, defined as a reduction in HbA1c of at least 11 mmol/mol (1.0%) and weight loss of at least 3% of initial body weight at six months
ALC, approved by the U.S