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In animals, Dox significantly increased systolic, diastolic, and mean arterial pressures, mitigated by EMPA or TRF individually, with no additive effect when combined

[PMID: 7588975] PubMed record related to this compound for laboratory literature review

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3.2.1 Nutrient Sensing and AMPK Activation IF reduces nutrient availability, leading to lower insulin levels and suppression of mechanical target of rapamycin (mTOR) signaling, a pathway that typically inhibits autophagy in the fed state