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But with that said, FDA-approved GLP-1s are much safer than compounded alternatives, so it is a good idea to switch to the name-brand medication when possible. He says that there are no strict guidelines on switching, but since the compounded medications are unregulated and dosing may be inaccurate, it is best to start at a low dose with physician supervision, and titrate the medication up per established recommendations

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During the early titration phase when GI symptoms may limit exercise tolerance, walking is often the only practical option

Thats something to keep an eye on. Other companies are developing once-a-month injectable formulations