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PMCID: PMC12815088

For example, in mice fed a 4% fat diet, short-term (4 weeks) or long-term (74 weeks) treatment with LA (20 mg/kg body weight) produced no improvement in systemic hypertriglyceridemia (HTG) and hepatic fat contents, and even significantly increased cholesterol content in rat livers despite enhanced mRNA expression of lipid oxidationrelated genes (fibroblast growth factor-21 [Fgf21], peroxisome proliferatorsactivated receptor alpha[ppar], acyl coenzyme A oxidase [acox1], carnitine palmitoyl transferase 1a and 2 [cpt1a and cpt2], recombinant retinoid X receptor a [rxra]), and ATP-binding cassette transporter A1 [abca1])

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The other benefits of vitamin B12 include the following: Improved metabolism Higher energy levels Better concentration Easier weight loss Enhanced immune system Accelerated hair growth Vitamin B12 Deficiency The best approach to tell if someone is vitamin B12 deficient is not to measure vitamin B12 levels in the blood because some deficient individuals can have regular vitamin B12 levels