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Future directions The reduction of inflammation is of fundamental importance in HFpEF treatment, as CRP was associated both with cardiovascular mortality and all-cause mortality in a recent meta-analysis [56]

Headache Dizziness Nausea Drowsiness Depression Mild Tremor Mild Anxiety Abdominal Cramps Irritability Reduced Alertness Confusion Low blood pressure According to the Mayo Clinic, headaches, dizziness, nausea, and drowsiness are the most common symptoms

In the liver, they both have metabolic regulation actions, but IRS-2 has a more profound role in lipid metabolism [121]

PMID 11695986

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