doi: 10.1146/annurev-biochem-062917-011852 27
Research demonstrates that acetyl-L-carnitine ameliorates insulin resistance through multiple mechanisms: restoring tissue carnitine levels in skeletal muscle and myocardium, improving mitochondrial -oxidation of fatty acids to reduce accumulation of lipotoxic intermediates, enhancing glucose disposal and oxidation capacity, and reducing inflammatory signaling that impairs insulin receptor function
The apolipoprotein E (APOE) genotype was determined using imputed genotypes of SNPs rs429358 (APOE 4) and rs7412 (APOE 2) 26,27
Your endocrine system responds to these signals the same way it did when you were younger, before age-related decline began eroding your baseline GH production by roughly 15% each decade after your thirties
PCs are a member of the former, along with PEs, phosphatidylserines (PSs), phosphatidylinositols (PIs), and cardiolipins (Li et al