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Unlike traditional GLP-1 agonists, which act on a single receptor pathway, GEP-44 functions as a triple agonist targeting GLP-1 alongside peptide YY receptors Y1 and Y2
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In the randomised trials, the average effects are real but moderate, and they come with a ketone signal that has to be respected.6 When these medicines cut insulin need quickly, insulin must be reduced proactively or hypoglycaemia follows
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