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Systematic studies further reveal that metformin confers significant preventive effects against endometrial, ovarian, and breast cancers [11, 102]
For context on where semaglutide sits within its class, the dual GLP-1/GIP agonist tirzepatide produced even larger average losses about 21% on its highest dose in the SURMOUNT-1 trial led by Ania Jastreboff in 2022
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