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About the Author: Jack Mountain, PharmD Jack Mountain, PharmD, is completing a post-graduate year two (PGY-2) pharmacy residency in ambulatory care at Rhode Island Hospital
The results showed that GLP-1R mutant E127 ECD CQ211 ECL1 C substantially decreased the potency (~100 times) of GLP-1 in the cAMP accumulation assay, which could be recovered by adding 1 mM of dithiothreitol (DTT) (Fig
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doi:10.15227/orgsyn.001.0079
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