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Pharmacogenetics 11, 399415

A meta-analysis of 26 RCTs (n=3,864) found that NAC (typically 600 mg twice daily) reduced the incidence of contrast-induced nephropathy by 40% (OR 0.60, 95% CI 0.44-0.81) (Gonzales et al., BMC Med, 2007) [67]

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The declining plasma concentration provides a quantitative framework for researchers designing dose-response studies, as physiologically relevant in vitro concentrations should bracket the 200-500 nM range to model the young-to-aged spectrum

Integrative Medicine: A Clinician's Journal, 13(1), p.8