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Despite its exclusive cytosolic production 5 , GSH is also abundantly present in many organelles including peroxisomes, the nucleus, ER and mitochondria 68

Specifically, research shows that Bifidobacterium adolescentis is a high GABA producer.[ref] Lactobacillus brevis DPC6108 and Lactobacillus rhamnosus are also probiotic strains that produce GABA.[ref][ref] A 2024 double blind placebo controlled trial found that a probiotic formulation of Lactobacillus brevis and Lactiplantibacillus plantarum reduced symptoms of depression and improved mood, but did not affect stress levels

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