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On the other hand, it efficiently delivers p65 siRNA to target and silence NF-B, thus reducing hepatocyte injury markers (ALT/AST), suppressing the release of inflammatory factors, and significantly ameliorating acute liver injury by targeting this central inflammatory pathway (Yin et al., 2023)
An imbalance in iron homeostasis can catalyze an overproduction of free radicals, setting off a cascade of pathological events [199]
Dec 2018;121(Pt 1):981-989
Mato JM, et al
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