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The mechanisms underlying taste perception changes during GLP-1 therapy are likely multifactorial and indirect rather than representing true gustatory dysfunction
This pharmacokinetic limitation prompted development of GLP-1RAs that maintain receptor engagement while resisting enzymatic degradation
Clinical trials have pointed out a neuroprotective effect and an improvement of clinical outcome for some anti-diabetic treatments, translating them into new therapies against neurodegenerative conditions, such as Alzheimers disease, dementia, or Parkinsons disease (Green et al., 2019
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